Intestinal Cell Defense Mechanism Against Bacteria: Molecular Mechanism of Selected Autophagy Elucidated

Salmonella is widely prevalent in the animal kingdom. The reason we do not suffer from severe intestinal infections very often is due to our body's defence system, which manages to digest invading bacteria. This is why, generally speaking, a healthy human being will only fall ill if he consumes more than 100.000 salmonella bacteria via a contaminated food source, such as eggs or meat.

An international team of researchers, led by Prof. Ivan Dikic from the Goethe University in Frankfurt has now found out how body cells recognise salmonella and render it harmless. Understanding this process at a molecular level is crucial in identifying new targets for treatment. Tropical and sub-tropical countries in particular, where various sub-species of salmonella are common, are experiencing a rapid increase in resistance to antibiotics, with children at greatest risk.....



Read full story in Science Daily.

Atomic-Scale Structures of Ribosome Could Help Improve Antibiotics: How Protein-Making Machine Bends Without Breaking

It sounds like hype from a late-night infomercial: It can twist and bend without breaking! And wait, there's more: It could someday help you fend off disease!

But in this case it's true, thanks to scientists from several institutions including the U.S. Department of Energy's Lawrence Berkeley National Laboratory. They derived atomic-scale resolution structures of the cell's protein-making machine, the ribosome, at key stages of its job....


Read Full Story in Science Daily.

• Dr. Richard G. Davis Of Precision Eye Care Brings Advanced Technology To Laser Refractive Cataract Surger | May 17, 2011
• Juvederm One Of Top Fillers To Restore Youthful Appearance | May 15, 2011
• Pennsylvania May Require Dna Samples For All Felony Arrests | May 13, 2011
• Uralchem Holding P.l.c. Reports Full Year 2010 Ifrs Financial Results | May 12, 2011
• Medical Guardian Announces New 911 Alert Device | May 12, 2011
• Rottenstein Law Group Evaluating Johnson & Johnson's Aggressive Acquisitions Despite Troubles With As | May 11, 2011
• Complex Landscape Of Third-party Extended Business Office Services Offerings Complicate Selection Process | May 10, 2011
• Vital Help For Snakebite Victims | May 10, 2011
• Howard G. Buffett Foundation Teams With Dupont And The Donald Danforth Plant Science Center To Deliver Nu | May 06, 2011
• Rottenstein Law Group Contemplates Inconsistent Messages From Zimmer Regarding Recall Of Nexgen Knee Comp | May 04, 2011

Evolutionary Adaptations Can Be Reversed, but Rarely

Physicists' study of evolution in bacteria shows that adaptations can be undone, but rarely. Ever since Charles Darwin proposed his theory of evolution in 1859, scientists have wondered whether evolutionary adaptations can be reversed. Answering that question has proved difficult, partly due to conflicting evidence. In 2003, scientists showed that some species of insects have gained, lost and regained wings over millions of years. But a few years later, a different team found that a protein that helps control cells' stress responses could not evolve back to its original form....

Read full article in Since Daily.